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[persephone_kore]

Squee! The third refinement of the H. marismortui large ribosomal subunit is out! (As of... Tuesday.)

Comments

[dreagoddess.livejournal.com]

Umm....yaaaaaaaaaaaaay!!!!!!!!!!!!!!!!! (I have NO idea what you just said, but it sounds like a yaaaay!!! moment. ;))

[rexlapinii.livejournal.com]

I second the yay and the incomprehension. Mine is an uncomprehending yay. But celebratory. Go you, H. marismortui, way to refine those subunits!

[persephone-kore.livejournal.com]

*gigglefits* Very quick version:

Ribosomes are the bits of cells that assemble proteins, which all sorts of other stuff gets done by/is made of.

The primary constituent of ribosomes are BIG HONKING MOLECULES of RNA.

Well, they're really big for molecules.

My thesis project involves looking at existing determined structures of RNA molecules, and is rather heavily dependent on their quality.

This structure is the single largest structure in the database. (Think a handful at a few thousand nucleotides each, as opposed to lots of midsize ones at about a hundred or so and lots of little ones under fifty.)

The lab I work in is mostly focused, lately, on evaluating and improving the determination of molecular structures.

In conclusion, we are really happy with the fact that the lab that did this structure is interested enough in improving it that they've recalculated with improvements twice now and are interested in doing it some more, instead of just leaving it. This is for multiple reasons:
1. Well, the basic one: they're interested in really getting it right. This is a good thing.
2. If we are going to have our statistics swamped by a monster structure, let it be a really good one! (Which it already was the first time, I should note. Now it is better.)
3. They're actually interested in incorporating some of our analysis and resulting suggestions in an eventual round, which if accomplished is something for us to brag about.

[persephone-kore.livejournal.com]

*grins* Yes, it is.

I posted what was supposed to be a very quick version in response to Alan's comment, but it got a bit out of hand.

Even quicker version: The lab responsible for an RNA structure my work is rather dependent on just put out a new and improved version of it, and now I can play with the new one.

[dreagoddess.livejournal.com]

Ohhhhhhhhhhhhh! In that case, completely comprehending yaaaaaaaaaaaaaaay!!!!!!!!!! ;)

[persephone-kore.livejournal.com]

:)